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4.7 / 5

A Berlin preventive-medicine clinic where the clinician thinks beyond the panel and the year-on-year retest actually catches change.

Clinic · Berlin Annual check-up Bioscientia labs Conflict of interest

What YEARS is.

YEARS is a private preventive-medicine clinic in Berlin. The product is a structured annual check-up: a full day of testing (cardiology, pulmonology, body composition, neurocognitive battery, HRV, vision/hearing, skin scan), a complete blood and stool panel through Bioscientia, and a clinician-led debrief that turns the data into a personalised plan. Year two is a retest against year one with the plan adjusted.

Comparable in shape to the early Cleveland HeartLab visits or the Human Longevity-style executive checkups, but routed through Germany's private healthcare system at a price-point closer to a high-end annual gym membership than to a US executive physical.

What YEARS actually found.

Four things conventional medicine and the consumer testing services on this list had all missed:

  1. Lipoprotein(a) genetic mutation — at 256 nmol/L, well into the high-risk zone. This is genetic and lifelong; missing it in a 24-year-old is the kind of oversight that costs decades.
  2. VO₂max well below age and lifestyle prediction — first CPET returned >33 ml/kg/min. For a male in his twenties who lifted regularly, that was a flag, not a baseline.
  3. HOMA-IR drifting toward insulin resistance — 2.8 at the first check, in a slim 24-year-old. Caught early, corrected by year two (2.3).
  4. HRV stress-response near the floor of the reference population — Tonus axis at the 2nd percentile, Stress Index at the 5th. The data piece that caught my panic disorder before the diagnosis came in.

Dr. medic Alexandru Ardelean ran the debrief and built the plan around all four findings. The full year-one to year-two delta is the substance of the H1 2026 drop — every claim above is a real, dated lab value that anyone can audit on that page.

The experience.

Clinic day is ~5 hours. The phlebotomist drew cleanly; the CPET was a real maximal-effort test, not a token treadmill walk. The HRV measurement was a 10-minute supine read with proper electrodes and a signal-quality check, not a wrist-worn estimate. Body composition is BIA + skinfolds, not a fancy DEXA — adequate for tracking, not the gold standard.

The debrief is what most longevity products lack and what YEARS does well. Dr. Ardelean read the full panel, walked me through what each cluster of markers told a story about, and translated "elevated this, low that" into a coherent plan with explicit targets and retest windows. The contrast with Function Health's app-driven "your levels are out of range" boilerplate is enormous.

Pros

  • Clinician who reads the panel as a system, not a checklist
  • Caught Lp(a), low VO₂max, HOMA-IR drift, and a near-floor HRV stress response
  • Year-on-year retest produced measurable improvement (calprotectin 434→9, ApoB 93→84, VO₂max 33→42, HRV every axis up)
  • Bioscientia-backed assays — clinical-grade, not direct-to-consumer mass-market
  • Plan was hyper-personalised with explicit targets and retest cadence
  • Treats the year-on-year delta as the product, not the snapshot

Cons

  • Final deliverable is still a 60-page PDF in 2026 — should be a live dashboard you can return to between visits
  • Berlin-only; no remote option for patients outside the EU yet
  • Pricing is private healthcare, not insurance-reimbursed — not for everyone
  • No public review programme — you can only judge by patient testimonials

Who it's for.

If you're in Germany, the EU, or willing to fly to Berlin once a year, and you want one place that integrates labs + cardio testing + body comp + neurocognitive + clinician judgement into a single year-on-year picture, YEARS is the closest thing I've found in Europe. Function Health is broader and cheaper but app-mediated; YEARS is narrower-but-deeper and clinician-mediated. Different products solving different problems.

If you want a remote-first, app-led product, look at Function Health (US) or Aware (DE) instead. If you want a comprehensive in-person preventive workup with a clinician, this is the highest-quality option I've personally used.

Verdict · 4.7 / 5

Highest-rated service on the list, calibrated for the obvious COI. Half a star docked for the PDF-only deliverable in 2026. Would and do recommend to family — the same data anchors the rest of this site, so my biases are paid for in the open.


Reviewed by Niko Hems · Last updated · Two annual check-ups completed (Feb 2025, Jan 2026)