The verdicts at a glance.

Best for clinical depth
YEARS
4.7/5 · COI
Best for US access
Function Health
4.0/5 · 100+ markers
Best EU entry point
Aware
3.8/5 · curated panel
Skip / wait
SelfDecode · Blueprint test
2.0/5 each

Sorted by score, highest first. Each card links to the full review with pros, cons, who it's for, and what I'd actually recommend doing instead — when there is a better option.

#1
4.7
/ 5

YEARS clinic

A Berlin preventive-medicine clinic with a clinician who actually thinks beyond the panel. Found my Lp(a) mutation, my low VO₂max, my early insulin-resistance trend, and my dead HRV stress-response — and built a year-one plan that delivered measurable improvement.

Conflict of interest
Clinic · Berlin · Annual Read review
Function Health logo #2
4.0
/ 5

Function Health

Excellent breadth (100+ biomarkers, twice yearly) at the best mass-market price point. The catch: the testing experience under the hood is just Quest Diagnostics, and the app's insights skew broad-and-shallow rather than actionable.

US · Subscription · Quest-backed Read review
#3
3.8
/ 5

Aware

The Function Health of Germany. Curated, smaller panel of biomarkers that actually matter — sensible price point and the cleanest entry into preventive testing for EU users. Cooling note: their product has barely moved in two years while US peers expand monthly.

DE · Subscription · Curated panel Read review
#4
2.0
/ 5

SelfDecode

Genotype intelligence with a serious editorial problem. Solid clinical findings (it correctly flagged my Lp(a) and ApoE) sit next to pseudoscientific recommendations from animal studies in the same UI — undifferentiated by evidence weight. Information overload by design.

SaaS · DTC genetics · Subscription Read review
Blueprint Protocol #5
2.0
/ 5

Blueprint microplastics test

The actual home test kit, not the protocol. A finger-prick blood collection kit that needs more blood than a finger-prick comfortably yields, returns numbers no one yet knows what to do with. Skip until clinical interventions exist or until they switch to venous draw.

Home test · Microplastics · One-off Read review

How the scores work.

Each review weighs five things: testing experience (the chair, the sample, the wait), data quality (assay choice, reference ranges, reproducibility), insight quality (does the platform actually help me act on the data?), price-to-value, and direction of travel (is the company shipping or stagnant?). Scores are mine, calibrated against a year of using all five against each other on the same body.

I am not a clinician, a regulator, or a Consumer Reports analyst. These are the same lens I look at every other intervention through on this site — measured, single-subject, and explicit about the confounds. If you've used any of these and saw something different, tell me: niko@nikohems.de. I'll publish revisions when warranted.


Last updated: . Reviews are revised as I run additional retests or when a service ships a meaningful change.